Anatoly I. Bozhkov
Position:
Head of the Department of Molecular Biology and Biotechnology
Director of the Research Institute of Biology, V. N. Karazin Kharkiv National University
Academic Degree:
Doctor of Biological Sciences (D.Sc. in Biology)
Specialization: 03.00.04 – Biochemistry
Academic Title:
Professor
Languages:
English
Research Profiles:
e-mail: niibio@karazin.ua
Molecular Biology
Biotechnology
Introduction to the Degree Programme
Cell Biology
Introduction to Molecular Biology
Modern Nano- and Biocognitive Technologies: Perspectives for Healthy Ageing and Socio-Biological Challenges of Ageing
Molecular and genetic mechanisms underlying biological ageing, longevity, and age-related diseases;
Metabolic, biochemical, and epigenetic regulation during ageing and adaptation to environmental stress;
Oxidative stress, mitochondrial dysfunction, redox regulation, and cellular signalling pathways;
Molecular mechanisms of liver fibrosis, tissue regeneration, and chronic disease progression;
Development and biological evaluation of natural and synthetic bioactive compounds for medical and veterinary applications;
Pharmaceutical biotechnology, including nanobiotechnology, targeted drug delivery systems, and translational biomedical research;
Biotechnology of microalgae, including the cultivation of Dunaliella viridis, Chlorella, and other microalgal species, as well as the discovery and characterization of biologically active natural compounds;
Bioinformatics and computational biology, including molecular docking, molecular dynamics simulations, structural modelling of proteins, peptides, and nanocarriers, analysis of next-generation sequencing (NGS) and multi-omics datasets, development of artificial neural networks and machine learning models, programming in Python and R, development of bioinformatics software and computational pipelines, and the application of artificial intelligence and deep learning to biomedical research.
Vice President of the Scientific Medical Society of Gerontologists and Geriatricians of Ukraine;
Member of the Ukrainian Biochemical Society;
Member of the Ukrainian Society for Cell Biology;
Chair of the Kharkiv Regional Branch of the Ukrainian Society for Cell Biology;
Chair of the Kharkiv Regional Branch of the Scientific Society of Gerontologists and Geriatricians of Ukraine.
Member of the Editorial Board of Algologia;
Co-Editor of the international scientific journal Ageing and Longevity.
Author of:
more than 300 peer-reviewed scientific publications;
3 university textbooks;
2 scientific monographs.
Bozhkov, A., Batuieva, Y., Klimova, E., Ganin, V., Ivanov, I., Bondar, A., ... & Bozhkov, A. (2025). The choice of strategy for the regeneration of excision wounds is determined by age-dependent structural and functional characteristics of the organism. Ageing and Longevity, 6(4), 293–314.
Bozhkov, A., & Verkhratsky, A. (2025). Bioengineering of Mental Health, Cognitive Longevity and the Challenges of Ageing. Ageing and Longevity, 6(4), 260–263.
Ivanov, E. G., Klimova, E. M., Bozhkov, A. A., Kovalova, M. K., & Bozhkov, A. I. (2025). Сomponents of colostrum regulate the activity of the immune system in animals with liver fibrosis. Regulatory Mechanisms in Biosystems, 16(4), e25176.
Bozhkov, A. (2025). Studies on the mechanisms of ageing using the calorie-restricted diet model: A retrospective analysis of the research conducted by the Kharkiv Ontophysiological School. Ageing and Longevity, 6(3), 212–235.
Bozhkov, A., & Verkhratsky, A. (2025). Mechanisms of Ageing: Patterns and Idiosyncrasies. Ageing and Longevity, 6(3), 181–184.
Bozhkov, A., Akzhyhitov, R., & Dobrianska, N. (2025). Challenges in Experimental Gerontology: Are Solutions Possible? On the Calculation of Xenobiotic Doses. Ageing and Longevity, 6(2), 101–110.
Bozhkov, A., Tolstun, D., Shershanova, H., & Verkhratsky, A. (2025). New look, new perspectives. Ageing and Longevity, 6(1), 98–100.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Yefimova, S. L., ... & Bozhkov, A. I. (2025). Geroprotective effects of GdVO4:Eu3+ nanoparticles, metformin and calorie restriction in male rats with accelerated aging induced by overnutrition in early life. Biogerontology, 26(1), 14.
Bozhkov, A., Akzhyhitov, R., Dobrianska, N., & Bozhkov, А. (2024). Old rats are not inferior to young ones in their ability to adapt to repeated sequential exposure to copper sulfate pentahydrate. Ageing and Longevity, 5(4), 198–219.
Bozhkov, A. (2024). Do we get sick because we are getting old, or do we get old and therefore get sick? Kharkiv Gerontological School—eighty years later. Ageing and Longevity, 5(4), 224–244.
Bozhkov, A., & Verkhratsky, A. (2024). To Authors and Readers. Ageing and Longevity, 5(4).
Bozhkov, A. I., Bobkov, V. V., Osolodchenko, T. P., Yurchenko, O. I., Ganin, V. Y., ... & Bozhkov, A. A. (2024). The antibacterial activity of the copper for Staphylococcus aureus 124 and Pseudomonas aeruginosa 18 depends on its state: Metalized, chelated and ionic. Heliyon, 10(20).
Bozhkov, A., Lebid-Biletska, K., Ivanov, E., Bozhkov, А., & Nikitchenko, Y. (2024). Hepatotoxic doses of copper sulfate induce metabolic memory in the redox system, which has an age-dependent nature. Ageing and Longevity, 5(3), 113–128.
Ivanov, E. G., Lebid-Biletska, K. M., Bozhkov, A. I., & Nikitchenko, Y. V. (2024). Copper sulfate and carbon tetrachloride induces a uniform response at the level of the redox system and the nature of this response depends on age. Regulatory Mechanisms in Biosystems, 15(3), 496–503.
Ivanov, E., Akzhyhitov, R., & Bozhkov, A. (2024). Components from various biological sources reduces the toxic effects of copper sulphate in old animals. Collection of Scientific Papers «ΛΌГOΣ», 191–199.
Bozhkov, A. I., Akzhyhitov, R. A., Bilovetska, S. G., Ivanov, E. G., Dobrianska, N. I., ... & Bozhkov, A. A. (2024). The effect of retinol acetate on liver fibrosis depends on the temporal features of the development of pathology. Journal of Clinical and Experimental Hepatology, 14(3), 101338.
Ivanov, I., Bondar, A., & Bozhkov, A. (2024). Age-dependent features of the bone marrow response to toxicogenic liver fibrosis in the experiment. Collection of Scientific Papers «ΛΌГOΣ», 126–134.
Bozhkov, A. A., Ganin, V. Y., Akzhyhitov, R. A., Ivanov, E. G., Bilovetska, S. G., ... & Bozhkov, A. I. (2024). Chlorogenic acid from sunflower meal regulates the number of immunocompetent cells in animals with toxic liver fibrosis. Clinical Nutrition Open Science, 53, 78–94.
Ivanov, E. G., Goltvyansky, A. V., Bozhkov, A. I., & Gromovoy, T. Y. (2024). Selective-integrative technology for the separation of colostrum into components and the possibilities of obtaining protein substances from different sources. Igor Sikorsky Kyiv Polytechnic Institute.
Bozhkov, A. I., Dobrianska, N. I., Akzhyhitov, R. A., Novikova, V. V., Haiovyi, S. S., ... & Bozhkov, A. A. (2024). Young and old animals “use” different strategies for adapting to the chronic effects of ethanol. Translational Medicine of Aging, 8, 1–11.
Bozhkov, A., Bobkov, V., Skrypnyk, A., Osolodchenko, T., & Ponomarenko, S. (2023). Thin-film copper coatings have antibactericidal effect. Collection of Scientific Papers «ΛΌГOΣ», 101–105.
Bozhkov, A., & Bilovetska, S. (2023). Vitamin A accelerates the process of liver regeneration in the initial stages of Сu-induced fibrosis. ScienceRise: Biological Science, 34–39.
Bilovetska, S., & Bozhkov, A. (2023). Vitamin A accelerates the process of liver regeneration in the initial stages of Cu-induced fibrosis. ScienceRise: Biological Science, 36(3).
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Yefimova, S. L., ... & Bozhkov, A. I. (2023). CeO2 nanoparticles improve prooxidant/antioxidant balance, life quality and survival of old male rats. Biogerontology, 24(1), 47–66.
Haiovyi, S., & Bozhkov, A. (2023). Hormetic effect on the toxic action of copper ions depends on the tissue distribution of copper ions. Grail of Science, 157–162.
Нікітченко, Ю. В., Клочков, В. К., Кавок, Н. С., Карпенко, Н. О., Сєдих, О. О., ... & Божков, А. І. (2023). Порівняльна ефективність антивікового впливу наночастинок ортованадату, метформіну та калорійно обмеженої дієти при експериментальному прискореному старінні щурів. Доповіді Національної академії наук України, 49–58.
Klimova, E. M., Bozhkov, A. I., Lavinska, O. V., Drozdova, L. A., & Kurhuzova, N. I. (2023). Low molecular weight cytotoxic components (DAMPs) form the post-COVID-19 syndrome. Immunobiology, 228(1), 152316.
Bozhkov, A. I., Novikova, V. V., Klimova, E. M., Ionov, I. A., Akzhyhitov, R. A., ... & Bozhkov, A. A. (2023). Vitamin A reduces the mortality of animals with induced liver fibrosis by providing a multi-level body defense system. Journal of Clinical and Experimental Hepatology, 13(1), 48–63.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Nikitchenko, I. V., ... & Bozhkov, A. I. (2022). Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats. Biological Trace Element Research, 200(3), 1237.
Bozhkov, A., Ionov, I., Kurhuzova, N., Novikova, A., Katerynych, О., ... & Bozhkov, A. (2022). Vitamin A intake forms resistance to hypervitaminosis A and affects the functional activity of the liver. Clinical Nutrition Open Science, 41, 82–97.
Moskalov, V., Melnychenko, S. Y., & Bozhkov, A. I. (2022). Dose dependence of hepatoprotective activity of mesenchymal stem cells exometabolites. 2022.
Bozhkov, A. I., Ohiienko, S. L., Bondar, A. Y., Katrich, V. O., Kozheshkurt, V. O., ... & Bozhkov, A. A. (2021). The Electrical Conductivity of Bone Marrow Cells Suspension Associated with Proliferative Activity and Depends on the Donor’s Age and the Functional Activity of the Liver. Cell Biochemistry and Biophysics, 79(4), 823–831.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Averchenko, K. A., Karpenko, N. A., ... & Bozhkov, A. I. (2021). Anti-aging effects of antioxidant rare-earth orthovanadate nanoparticles in Wistar rats. Biological Trace Element Research, 199(11), 4183–4192.
Bozhkov, A. I., Bozhkov, A. A., Ponomarenko, I. E., Kurguzova, N. I., Akzhyhitov, R. A., ... & Nikitchenko, Y. V. (2021). Elimination of the toxic effect of copper sulfate is accompanied by the normalization of liver function in fibrosis. Regulatory Mechanisms in Biosystems, 12(4), 655–663.
Bozhkov, A. I., Ohiienko, S. L., Ivanov, E. G., Bondar, A. Y., & Kot, Y. H. (2021). Determination of Electromagnetic Radiations and Liver Fibrosis Influences the “Lifespan” of Bone Marrow Cells. Recent Developments in Medicine and Medical Research, 1, 37–51.
Kozheshkurt, V., Bozhkov, A., Ohiienko, S., Bondar, A., Katrych, V., Novikova, A., ... & Bozhkov, A. (2021). Electrical Conductivity of Bone Marrow Cell Cultures and Their Connection with Proliferative Activity: Age Aspect. Trends in Sciences, 18(19), 5–5.
Bozhkov, A., Ivanov, I., Klimova, E., Kurguzova, N., Bozhkov, А., Goltvyanskiy, A., ... & Nikitchenko, Y. (2021). “Mix-Factor” is involved in the regulation of the organism's redox systems in the late stages of ontogenesis and affects the lifespan of animals. Ageing and Longevity, 2(2), 24–36.
Ivanov, I., Kozheshkurt, V., Bozhkov, A., Goltvjansky, A., Katrich, V., Sidorov, V., ... & Bozhkov, A. (2021). Low-molecular components of colostrum as a regulator of the organism redox-system and biological antidote. EUREKA: Life Sciences, 56–64.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Yefimova, S. L., ... & Bozhkov, A. I. (2021). Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria. Biological Trace Element Research, 199(3), 1213–1213.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Yefimova, S. L., ... & Bozhkov, A. I. (2021). Age-related effects of orthovanadate nanoparticles involve activation of GSH-dependent antioxidant system in liver mitochondria. Biological Trace Element Research, 199(2), 649–659.
Bozhkov, A. I., Sidorov, V. I., Alboqai, O. K., Akzhyhitov, R. A., Kurguzova, N. I., ... & Bozhkov, A. A. (2021). The role of metallothioneins in the formation of hierarchical mechanisms of resistance to toxic compounds in young and old animals on the example of copper sulfate. Translational Medicine of Aging, 5, 62–74.
Novikova, A., Ivanov, E., Kurguzova, N., Akzhigitov, R., & Bozhkov, A. (2021). Colostrum components involved in regulating the number of immunocompetent cells in animals with liver fibrosis. Norwegian Journal of Development of the International Science, 3–11.
Kozheshkurt, V., Ivanov, I., Antonenko, Y., Katrich, V., Bozhkov, A., & Gromovoy, T. (2021). Devising an express method for estimating the quality of colostrum and its components based on electrical conductivity. Східно-Європейський журнал передових технологій, 69–77.
Antonenko, Y. A., Kozheshkurt, V. A., Shtoda, D. A., Katrich, V. A., & Bozhkov, A. I. (2020). Electromagnetic sensor for measuring the dielectric permeability of materials. Visnyk of V.N. Karazin Kharkiv National University, series “Radio Physics and Electronics”.
Нікітченко, Ю. В., Клочков, В. К., Кавок, Н. С., Карпенко, Н. О., Сєдих, О. О., ... & Божков, А. І. (2020). Наночастинки ортованадату гадолінію збільшують виживаність старих щурів. Доповіді Національної академії наук України, 29–36.
Антоненко, Є. О., Кожешкурт, V. О., Штода, Д. О., Катрич, В. О., & Божков, А. І. (2020). Електромагнітний сенсор для вимірювання діелектричної проникності матеріалів. Вісник Харківського національного університету імені В. Н. Каразіна. Серія Радіофізика та електроніка, 22020.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Sedyh, O. O., ... & Bozhkov, A. I. (2020). Cerium oxide nanoparticles and metformin increase the reliability of the prooxidant/antioxidant balance and the survival of ageing rats. Доповіді Національної академії наук України, 35–44.
Bozhkov, A. I., Ohiienko, S. L., Bondar, A. Y., Ivanov, E. G., & Kurguzova, N. I. (2020). Low-molecular weight components of cow colostrum regulate bone marrow functions by modelling the redox-system of the organism. Regulatory Mechanisms in Biosystems, 11(2).
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Sedyh, O. O., ... & Bozhkov, A. I. (2020). Orthovanadate nanoparticles delay the accelerated aging in rats via the prevention of oxidative disturbances. Dopov. Nac. Akad. Nauk Ukr, 7, 43–51.
Bozhkov, A. I., Kovalova, M. K., Azeez, Z. A., & Goltvjansky, A. V. (2020). The effect of pre-sowing seed treatment on seedlings growth rate and their excretory activity. Regulatory Mechanisms in Biosystems, 11(1), 60–66.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Sedyh, O. O., ... & Bozhkov, A. I. (2020). Gadolinium orthovanadate nanoparticles increase survival of old rats. Dopov. Nac. Akad. Nauk Ukr, 2, 29–36.
Bozhkov, A. I., Kovaleva, M. K., Goltvyanskiy, A. V., Ushakova, E. O., Tsapko, H. Y., ... & Bozhkov, A. A. (2020). Preliminary Adaptation of Dunaliella viridis Strains to Copper Sulfate Affects the Thermal Stability of the Culture. International Journal on Algae, 22(1).